We would like to show you a description here but the site wont allow us. Spinal disc herniation is an injury to the cushioning and connective tissue between vertebrae, usually caused by excessive strain or trauma to the spine. Sciatica is a commonly used term to indicate pain radiating. Herniated nucleus pulposus is a condition in which part or all of the soft, gelatinous central portion of an intervertebral disk is forced through a weakened part of the disk, resulting in back pain and nerve root irritation. Advanced glycation end products in degenerative nucleus. Standardisation of basal medium for reproducible culture. This journal feature begins with a case vignette highlighting a common. Current strategies for management of intervertebral disc. In between them are soft disks filled with a jellylike substance. Free publisher full textpmc free full textpmc free pdf. On examination of the literature dealing with the nucleus pulposus and the conditions of vertebral epiphysitis and osteo chondritis, it is evident that a proper appreciation of certain radiological appearances in the spine calls for familiarity with the anatomy, function and pathology of the nucleus pulposus. The disk material may include elements of the nucleus pulposus, annulus fibrosus. Nucleus pulposus the nucleus pulposus of a nonimpaired young adult 2030 years of age consists of an ovalshaped, highly hydrated gelatinous materia1. The lumbar spine comprises the 5 vertebrae that are below the thoracic vertebrae and.
Clinical outcomes of patients treated with percutaneous. Cell sources for nucleus pulposus regeneration cell sources for nucleus pulposus regeneration kregar velikonja, nevenka. The effect of laser irradiation for nucleus pulposus. The precise cause of back pain is largely unknown, but degeneration of the intervertebral disc has been implicated as a possible source. Hydrated nucleus pulposus herniation in seven dogs. The lumbar spine is made up of 5 load transferring bones called vertebrae. Hernia nukleus pulposus pendahuluan hernia nukleus pulposus hnp merupakan salah satu penyebab dari nyeri punggung npb yang penting. While mechanical compression is still presumed to be of major importance, 24 leakage of nucleus pulposus np from the disc core onto nervous tissue may. The purpose of this study is to investigate the effect of ages in the degeneration process of diabetic nucleus pulposus np in rats and humans. Structure and function of the lumbar intervertebral disk.
The tear causes pain because of the nerves in the disk, and when the disk impinges on an adjacent nerve root, a segmental radiculopathy with paresthesias and weakness in the distribution of the affected root results. Diabetes mellitus dm has been clinically proved as a risk factor of disc degeneration, and the accumulation of advanced glycation end products ages is known to be potentially involved in diabetes. Herniasi diskus intervertebralis ke segala arah dapat terjadi akibat trauma atau stress fisik. Percutaneous laser disc decompression pldd was introduced for the treatment of lumbar disc hernias in the 1980s.
Obesity increases the risk of recurrent herniated nucleus pulposus after lumbar microdiscec. Saraf terjepit lainnya di sebabkan oleh keluarnya nukleus pulposus. Pdf nucleus pulposus herniation statpearls ncbi bookshelf. The most conclusive diagnostic tool for disc herniation is mri, and treatment may range from painkillers to surgery. Hernia nucleus pulposus hnp adalah suatu penyakit, dimana bantalan lunak diantara ruasruas tulang belakang soft gel disc atau nukleus pulposus mengalami tekanan dan pecah, sehingga terjadi penyempitan dan terjepitnya uraturat saraf yang melalui tulang belakang kita. Pubmed journal articles for nucleus pulposus herniated were found in prime pubmed. The nucleus pulposus is a mucoid protein that binds approximately three times its weight in water and allows for distribution of forces. These disks cushion the vertebrae and keep them in place. Herniated lumbar disc north american spine society. Prime pubmed nucleus pulposus herniated journal articles from. Herniation of the calcified nucleus pulposus is a rare complication, possibly producing minor symptoms and alarming roentgenographic findings which suggest the need for neurosurgical intervention. Percutaneous lumbar discectomy, percutaneous microdiscectomy, percutaneous mechanical disc decompression, lumbar herniated nucleous pulposus, radiculopathy abstract introduction. Orthopaedic physical therapy secrets third edition, 2017. Bulging disk, compressed disk, herniated intervertebral disk, herniated nucleus pulposus, prolapsed disk, ruptured disk, slipped disk.
The diagnosis has been largely presumptive, although supported in some cases by findings at surgery. Berolahraga secara teratur, terutama jenis olahraga yang dapat menguatkan otot serta sendi di tungkai dan punggung, misalnya berenang. Presumptive acute noncompressive nucleus pulposus extrusion in 11 cats. Differential ct diagnosis of extruded nucleus pulposus. Definisi hernia nucleus pulposus hnp adalah turunnya kandungan annulus fibrosus dari diskus intervertebralis lumbal pada spinal canal atau rupture annulus fibrosus dengan tekanan dari nucleus pulposus yang menyebabkan kompresi pada element saraf. Indira gayle g rioroso bsn 42 batch 20 cavite state university disc hernation physiology herniated. The lifetime prevalence of degenerative disc disease ddd is very high. The use of traction does not justify hospital admission. Herniated nucleus pulposus hnp is one of the most common diseases of the spine.
Hernia of the nucleus pulposus the british journal of. Next step after insertion of the needle at the proper site is to dye the nucleus pulposus and the herniated mass by using indigo carmine, after dyeing the nucleus pulposus changes to blue color but the annulus figure 4. It is known that disc degeneration begins with changes in the biochemical content of the nucleus pulposus. The natural history of herniated nucleus pulposus with. Hydrated nucleus pulposus extrusion hnpe is a cause of cervical myelopathy in nonchondrodystrophic and chondrodystrophic dogs beltran et al. Pencegahan hernia nukleus pulposus hnp meski hnp tidak selalu dapat dicegah, anda bisa mengurangi risiko saraf kejepit dengan melakukan langkahlangkah berikut. Treatment modalities for lumbar herniated discs that.
Pdf nucleus pulposus herniation is the most common cause of sciatic pain and one of the most common indications for spine surgery. Nucleus pulposus is the jellylike substance in the middle of the intervertebral disc. In this study of 100 cases in which a herniated nucleus pulposus was removed, all patients had sciatic pain, and, with one exception. The stimulation of lymphocytes by nucleus pulposus in patients with degenerative disk disease of the lumbar spine. Herniation of nucleus pulposus definition of herniation. Hernia nukleus pulposus hnp atau potrusi diskus intervertebralis pdi adalah suatu keadaan dimana terjadi penonjolan pada diskus intervertebralis ke dalam kanalis vertebralis protrusi diskus atau ruptur pada di s kus vebrata yang diakibatakan oleh menonjolnya nukleus pulposus yang menekan anulus fibrosus yang menyebabkan kompresi pada syaraf, terutama. The detection and differential diagnosis of extruded free disk fragments by ct has not been described in detail. Radiologic findings included erosion andor fracture of the anterior aspect of the vertebra, usually with interspace narrowing. The nucleus pulposus consists of collagen fibrils, proteoglycan. Degeneration of the intervertebral disc ivd is a natural process occurring during ageing and is under continuous investigation.
The journal of bone and joint surgery british volume. They are stacked in a column with an intervertebral disc sandwiched between each set of vertebrae. Autoimmune response to nucleus pulposus in the rabbit. The intervertebral disc consists of an inner nucleus pulposus np and an outer annulus fibrosus af. Cramer, in clinical anatomy of the spine, spinal cord, and. In this study of 100 cases in which a herniated nucleus pulposus was removed, all patients had sciatic pain, and, with one exception, all had back pain. In brief, the nucleus pulposus, a remnant of the notochord, is a soft gelatinous oval or beanshaped mass found in the centre of each intervertebral disc. A prospective study disclosed eight patients three children and five adults with anterior herniation of the nucleus pulposus ahnp. It functions to distribute hydraulic pressure in all directions within each disc under compressive loads. A spine fusion was done at the time of removal of the herniated nucleus in eightythree cases.
Cell sources for nucleus pulposus regeneration, european. Hnp causes hernia nucleus pulposus darling nuban the hydraulic effect hernia nukleus pulposus the contained, hydrated nucleus within the annulus acts as a shock absorber to cushion the spinal column from forces that are applied to. I ntervertebral disc hernia was first described by mixter and barr, 1 and the ensuing pain has been suggested to arise as a result of the mechanical compression that a ruptured disc exerts on adjacent nerves. Over 90% of over age 50 show radiographic signs of ddd in magnetic resonance imaging studies. A disc with a herniated nucleus pulposus can almost always be managed or fully repaired through proper treatment. It is composed of a thin lattice of collagen fibers. The ivd is a cartilagelike tissue and consists of two.
The author presents 4 cases in which spontaneous resorption of the herniated nuclear material and remission of symptoms occurred with conservative. Low back pain is the second leading cause of doctor visits each year, afflicting over 65 million americans. The most frequent cause of a herniated nucleus pulposus is agerelated degeneration that develops over time as the spine bears the strain and stress of everyday life. It is under pressure and has a migratory character. Your backbone, or spine, is made up of 26 bones called vertebrae. It may result in back pain, pain or sensation in different parts of the body, and physical disability. Hernia nucleus pulposus hnp hernia nucelus pulposus hnp adalah suatu nyeri yang disebabkan oleh proses patologik dikolumna vertebralis pada diskus intervertebralis diskogenik harsono, 1996. The clinical outcome is generally favourable with either medical or surgical management, but followup. Mechanical compression and nucleus pulposus application on. Hasan sadikin general hospital bandung indonesia article pdf available june 2015 with 2,123 reads how we measure reads.
295 236 1467 593 527 95 1436 54 637 288 702 1051 1382 609 105 418 539 1025 212 169 164 150 629 139 1276 913 534 115 397 420 511 860